Bird Flu Symptoms

Judging from the gradual tailing off of visitors to my bird flu symptoms page, it’s almost as if people have already forgotten the hype. This is probably mainly due to reduced exposure to bird flu in the mainstream press, and as they say no news, is good news.

Regardless, the science behind the scenes goes on and you can read my feature on the Tamiflu shortage in Nature online this week.

Meanwhile, news just in points to mutations in the viral polymerase gene as explaining how strains of influenza can jump the species barrier. According to Juergen Stech of the Institute of Virology in Marburg, Germany, writing in this week’s PNAS, polymerase mutations may be a pre-requisite to a pandemic, although he also points out that although convergent evolution in the polymerase gene plays a role, polymerase is not the whole story.

The mainstream media is quiet on the bird flu front at the moment, for as long as it stays that way, we’re probably flu free.

Search PubChem for Gluconic Acid

Several readers hit the sciencebase.com site searching for gluconic acid. This sugar-like compound occurs naturally in fruit, honey and wine and is used industrially as an acidity regulator in food and drink (E574). It is also used in cleaning products to remove mineral deposits (it is a strong chelating agent for calcium, iron, aluminium, and copper).

Anyway, if you’re after more information and chemical structures of small molecules, you can find more than five million of them using the PubChem search box on ChemSpy.com

Cats aren’t all good

Toxic metals emitted from automotive catalytic converters have been detected in urban air in the USA. The research was carried out by scientists in Sweden working with Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution.

The researchers discovered high concentrations of the elements platinum, palladium, rhodium and osmium in air over the Boston metropolitan area. Although these particles are not a serious health risk, evidence suggests they potentially could pose a future danger as worldwide car sales increase from an estimated 50 million in 2000 to more than 140 million in 2050.

Scientists have also detected elevated concentrations of these elements in Europe, Japan, Australia, Ghana, China and Greenland.

Finding ways to “stabilize” these metal particles within the converters “should be a priority to limit their potential impact,” says Sebastien Rauch of Chalmers University of Technology in Goeteborg.

Catalytic converters reduce noxious emissions of carbon monoxide, hydrocarbons, nitrogen oxides, and other pollutants, but as with all technology there is a counterpoint in this discovery of their constituent elements in the environment. Previously, UK researchers have investigated techniques that could be used to “mine” valuable heavy metals, such as platinum, from road run-off. Whether or not this kind of recycling could ever be viable or whether or not it would reduce atmospheric contamination is still wide open to discussion.

Hoodia gordonii

An extract of the succulent plant, Hoodia gordonii, with the seemingly cryptic name of P57AS3 (or P57 for short) has received a lot of media attention recently because this compound acts as a potent appetite suppressant. Indeed, trials have shown that it reduces daily calorie intake by 1000 kcal. According to Alok Jha writing in The Guardian on December 3, p57 has attracted the attention of food company Unilever having already been investigated by Pfizer and Cambridge-based Phytopharm. This begs the question, why? Surely, the last thing a company that manufactures icecream and such would want to suppress anyone’s appetite…

Anyway, a paper in the journal Brain Research describes p57 as a “steroidal glycoside” with “anorectic activity in animals”. Now, these are technical terms with precise definitions for professionals. Personally, I’d be cautious of taking a product that is essentially a steroid that triggers anorexia, wouldn’t you? Then again, the side-effects of obesity can be far worse. Just remember, if you’re chasing after this purportedly natural compound on the internet, that another infamous appetite suppressant, which goes by the name of cocaine is just as “natural”.

Girls Aloud find the right chemistry

Bet you never thought you’d see a kitchy, yet somehow chic, Brit girl band featuring in the Sciencebase blog!

Well, I couldn’t resist giving the waspish popsters Girls Aloud a mention because their new album due out this week is called “Chemistry”.

Polydor records who promote and press the band say: “Sarah, Nicola, Nadine, Kimberley and Cheryl have made a quirky British pop album. In a genre where girl bands dream of being Destiny’s Vogue, Girls Aloud have made an album that reflects what it’s like to be a 20-something girl living in the UK….blah, blah, blah….”

Like anyone cares, know what I’m sayin? All we really want, what we really, really want is to know that Chemistry also features the new hit single “Biology”.

My friends at the Institute of Physics must be kicking themselves that they didn’t get a mention, but I bet the permanantly poptastic Royal Society of Chemistry with its perpetual penchant for publicity will be rubbing its collective hands with glee as all those teenyboppers start sending in their application forms for membership. Grrrl power to the chemists!

Yeah, right, whateva, d’you fink I’m bovvered?

Black holes are intergalactic

According to a Cambridge U press release just in, the longest ever X-ray observation (1 million seconds) of a galaxy cluster proves that black holes can span intergalactic distances and actually block growth of the largest galaxies.

The Cambridge team has obtained new evidence that black holes are far more powerful cosmic entities than previously thought. Their influence can span vast distances, the researchers claim, heating the gas between galaxies and putting a restraining order on galactic size as stars can only form when gases cool. “It’s as if a heat source the size of a fingernail heats up a region the size of Earth,” team member Andrew Fabian explained.

Don’t you just love these comparisons? Why not say a gas fire heating up Jupiter instead, or an LED heating up the moon, or something equally unimaginable…oh well…the research replete with simile I assume is published in the December “Monthly Notices of the Royal Astronomical Society”. It’s like a single research paper illuminating a pan-galactic civilisation, or not as the case may be.

How to avoid colds and flu

These past few days I’ve felt rather listless, had vaguely aching limbs, a mild headache that comes and goes, and a dull, throbbing ache where I had my flu jab more than a month ago…could it be that I’ve actually caught flu, and that the vaccine has held off the worst of the symptoms? That throbbing pain at the site of the jab seems to be the smoking gun, but I’m not sure whether there is some persistent immune response at the site of an injection that might cause recurrent symptoms when one is struck subsequently by the live virus…

Anyone know for sure? I’d be interested in qualified comments

Meanwhile check out our practical tips on how to avoid colds and flu.