Totally tubular peptide rings

Posted at 12:00 am by David Bradley  

peptide nanotubesThe highly unique crystal structure of nanotubes constructed from cyclic peptides is revealed this month by Japanese researchers in the journal Organic Biomolecular Chemistry. The descendents of these novel nanotubes could find a role in future molecular electronic devices, according to the team, who allude to the high macrodipole moment of their materials.

Shunsaku Kimura and colleagues at Kyoto University, have built on the work of ETH’s Dieter Seebach and Wisconsin’s …

Solvent solution

Posted at 12:00 am by David Bradley  

ionic liquids (Credit: NIST)Interest in alternative solvents to replace volatile organic compounds is on the increase, so improved understanding of the properties of these alternatives is needed. One class of solvents researchers are keen to learn more about are the room temperature ionic liquids (RTILs). Researchers have commonly used absorption or fluorescence to study solvation properties. But now scientists in Japan, have carried out a Raman spectroscopic study of a series …

Cesamet, THC and chemotherapy

Posted at 3:03 pm by David Bradley  

The drug Cesamet (nabilone), a derivative of tetrahydrocannabinol, was “re-approved” for the clinical market this week for use in treating the side-effects of cancer chemotherapy, including nausea and vomiting. Genetic Engineering News reports that Valeant Pharmaceuticals International (NYSE:VRX) announced that the US Food and Drug Administration (FDA) has given marketing approval for Cesamet (CII) (nabilone) oral capsules. The drug interacts with the CB1 cannabinoid receptor found throughout the nervous system, its interaction with …

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