Canned heavy metal and more

My latest science news updates on SpectroscopyNOW – covering heavy metal sardines, pain relief and sleep problems, oral insulin and a new male infertility test that could explain the issue problem.

  • Canned heavy metal – Samples of tinned sardines, originating from six countries have been analyzed for total arsenic, cadmium, lead and mercury content using spectroscopy. The analysis provides a useful baseline for a foodstuff – small pelagic fish – that could become increasingly important in a possible sustainable future and shows that arsenic rather than mercury could be the main concern in eating such small fish rather than predators.
  • The near and FAAH of drug discovery – A new mathematical approach to drug discovery that can test a huge number of molecular structures using a computer only could uncover inhibitors for an important enzyme involved in sleep, pain and body movement.
  • Oral insulin microspheres – A simple, inexpensive, and gentle process to make tiny spheres of therapeutic proteins, such as insulin, might allow these agents to be delivered by mouth without the need to encapsulate them in a nanotech coating or other Trojan horse type system to get them past the hazards of the gastrointestinal tract and into the bloodstream.
  • Fertility testing issues circumvented by spectroscopic technique – Traditional clinical tests on seminal fluid for infertility and sub-fertility prediction do not provide many insights into the underlying medical problem. But, metabolic spectroscopic tests could offer a less time-consuming and less labour-intensive alternative to address this shortcoming and provide a non-invasive and more useful test for infertility that might hint at biological issues.

Making the web work for academia

The internet has changed fundamentally the way we communicate, the way we work, even the way we live our lives. That much is obvious to anyone who has ever shopped at Amazon, looked up a reference on PubMed, or gone social via Facebook. Those of us who’ve been using email and the wider world tools of web 1.0 and then web 2.0 since the 1990s have seen dot coms come and go, bubbles and egos inflate and then burst. There still exist luddites and every scare story about compromised privacy, Trojans, phishing attacks, wardriving (recently, most visible as the Firesheep plugin for Firefox), has those people running for their tinfoil hats and pulling the plug on their modems and routers.

Then there are organisations, such as academic institutions, that lack either the savvy or the will to overcome the inertia of cellulose-based bureaucracy. Some have taken tentative steps into the web 1.0 world and their legacy sites retain animated gifs proclaiming that they are “Under Construction” or “Copyright 1999” or worse still use ancient and long-discarded approaches to web design such as frames and the comic sans font that mark them out as stuck in the dark ages of the net. Obviously, some have moved forward slowly but surely and even have Twitter and Facebook badges and perhaps people engaging with the public via those pages. Few have adopted the web 2.0 ethic beyond the occasional reflected logo and graphical boxes with rounded-corners, and rarer still is the interactive feedback form or “corporate” blog section on an academic institution site.

Lyle Wetsch and Kristen Pike of the Memorial University of Newfoundland, Faculty of Business Administration, St. John’s, Newfoundland, Canada, point out that the same is sadly true of much of the commercial world, but there are many in that arena who have recognised the potential of web 2.0 not only to engage but to use the great resource that is the creativity and altruism of the audience.

In a paper that neatly sums up the problem entitled: “Marketing in a Web 2.0 world with a Web 1.0 mentality: the challenge of social web marketing in academic institutions”, the pair offer a new perspective for organisations. They suggest that, organisations and academic institutions hoping to employ social media and social networking technologies for mutual benefit must face the challenge of finding the right balance between utility and privacy.

“For a university especially, that balance is integral to ensuring that the technologies are being used and benefited from, and that the university stays away from any involvement in the technologies that could bring harm to its students, faculty and staff both online and offline,” the team says. After all, no one wants to see what Richard Dawkins gets up to at his laboratory Christmas Party on Facebook, nor do we want to hear what the Vice Chancellor had for breakfast and with whom.

The team points out that while the likes of Facebook are currenty flavour of the month, they are not immortal. Anyone remember Gopher? CompuServe? Geospaces? Indeed, information technology by its very nature is constantly evolving and reinventing itself. The Agora service of the 1990s used to retrieve and deliver early web pages via email, I saw this week that a similar service has just been invented that does pretty much the same thing as Agora did way back when, web2pdf.

“Educating individuals within the organisation or the university community about the good and the bad of social networking and social media technologies should be an important part of future efforts,” the team adds. They conclude that, “policies, recommendations, and also future efforts should be broad enough that they can move forward with the ever-evolving technologies…creating and facilitating the establishment and maintenance of communities should be the focus in order for universities to benefit.”

Lyle R. Wetsch, & Kristen Pike (2010). Marketing in a Web 2.0 world with a Web 1.0 mentality: the challenge of social web marketing in academic institutions Int. J. Electronic Marketing and Retailing, 3 (4), 398-414

Alcohol effects, giant testicles, pennycress

  • An alcoholic FAQ – Aspirin and other drugs prevent the enzyme alcohol dehydrogenase (found in the stomach and liver) from breaking down alcohol, thus slowing the liver’s ability to metabolise alcohol and so it accumulates in your blood faster and has longer-lasting effects, which means you get drunk faster and say drunk longer, but you will have an almighty hangover too (one that aspirin will not cure)
  • The biggest balls of all – The largest testicles by mass as a proportion of body mass are those of the bush cricket. According to behavioural ecologist Karim Vahed who has presumably had a good look, the tuberous bush cricket has testes accounting for 14% of its body mass.
  • Making pennycress pay its way – I’d never heard of this weed until today, but apparently, pennycress may have the potential to quell the food versus fuel debate. If initial findings prove true, it could become a biodiesel feedstock that doesn’t compete with corn and soybeans for acres. Field pennycress may be a new crop in development, but it’s an old weed. Thlaspi arvense is a winter annual weed known by farmers under several names–field pennycress, stinkweed, frenchweed–that grows widely across the Midwest. It isn’t considered a big weed problem because it completes its life cycle in late spring and doesn’t compete with newly planted corn or soybeans.
  • Benefits of statins explored – Among high-risk patients, lowering LDL cholesterol with high dose statin therapy reduces the risk of adverse outcomes such as heart attack and stroke more than standard statin treatment.
  • For those interested in alcohol rehabilitation, this is a site worth a look – http://www.michaelshouse.com/alcohol-rehab/

Pandemic flu watch results

Regular Sciencebase readers may recall that my family and I were recruited and took part in the participation in the 2009/2010 Flu Watch Project. During the whole period of the study we had just one cold or flu-like illness in the family, which was rather unusual for us. Personally, I almost reached the anniversary of not having had a cold until mid-October. Normally, I suffer at least 3 or 4 doses of man-flu during the year. Possibly down to my daily walk with the dog or just not getting out enough to be exposed to the viruses. Who knows?

Anyway, the Flu Watch team just sent back their findings from the survey about flu and what happened in the H1N1 pandemic. The survey and swabs we all sent back when we had a cold/flu revealed that 15-20% of the population are infected, children more commonly and the elderly less. On the whole, a large proportion of infections were accompanied by only very mild symptoms. One of the most startling findings was that despite our being in the midst of a pandemic, the amount of flu like illness and confirmed cases reported during the pandemic (2009/10) were similar to previous years.

The results also showed that people who regularly wash their hands with soap and hot water have a substantially lower risk of contracting flu. “This suggests that a lot of people catch flu by touching their mouth, eyes or nose with contaminated hands,” the team says. “We found that men were less hygienic than women and of course children were the least hygienic.”

Airbus A380 engine failure

Airbus A380 engine failure

  • A380 engine failure – Qantas flight 32 en route to Sydney, Australia, forced to make an emergency landing after an engine failure. Qantas has grounded all of its Airbus A380 “superjumobo” fleet as a result. There are 20 other A380s around the globe that have the same Rolls Royce engines as Qantas flight 32.
  • Rosalind Franklin and DNA: How wronged was she? – Watson, Francis Crick and Maurice Wilkins received the Nobel Prize in medicine or physiology in 1962 for this work, four years after Franklin’s death of ovarian cancer, possibly induced by her work with x-rays. But, shouldn’t Franklin’s work be given more credit than it has ever received. The debate goes on. To my mind, Wilkins let the crystallograph into W-C’s hands because they all suspected Pauling was on to the structure of DNA and Franklin was being too slow and cautious in making her pronouncements on it. As it turned out Pauling hadn’t come up with the correct structure anyway.

It’s a bug’s life

I briefly review Daniel Marlos’ latest book, Curious World of Bugs, in Six Sexy Science Books. But, I wanted to know more about the book and so offered Marlos a few questions on which he might wax lyrical.

What makes bugs such a fascinating subject?

Bugs make such a fascinating subject because they are ubiquitous. Bugs can be found all over the world in every conceivable environment. Unlike larger animals that flee when they are being observed, bugs couldn’t care less who is watching them and they are ready subjects to be photographed. Many children have a fascination with bugs, though sadly, most adults outgrow this initial reaction to the lower beasts.

What is the most remarkable bug?

This is of course my opinion, but I find the preying mantis to be the most remarkable bug. They are large and formidable predators. There is something almost human in their gestures and they will follow their prey or a larger predator by rotating their heads nearly completely around.

What’s the biggest? And prehistorically how does it compare to those giants of the past?

I would have to question a definition of biggest. The moth with the largest wingspan at twelve inches is the South American white witch. The moth with the greatest surface wing area is the Southeast Asian atlas moth. The longest insect is probably a walkingstick from Borneo that has been recorded at 14 inches long. The insect with the greatest mass is probably the African goliath beetle but the longest beetle is a South American longhorn beetle called a titan beetle that can cover the palm of an adult man, and that doesn’t include its substantial antennae. All of these are dwarfed by a prehistoric dragonfly that has been recorded in the fossil record as having a 30 inch wingspan.

Social insects are, in a sense, meta-organisms aside from our use of bees, do you think we could somehow engineer colonies to carry out other tasks?

Other than honey bees, I don’t think humans would have much luck tapping the social insect world to perform menial labour tasks. Wasps would sting and termites might eat our wooden homes. Ants would compete for food, so it seems we are limited to apiculture when it comes to having social insects perform a service for people.

Bugs will no doubt be here long after we as a species have burned outselves out, might there be a future with “intelligent” bugs?

Depending upon how intelligence is defined, there are numerous intelligent insects. Cockroaches can be taught to run a maze. Social insects like ants, bees, wasps and termites have a highly developed caste system and the individual will sacrifice for the good of the colony. Though social insects care for their young, they are not the only bugs to do so. Many spiders will defend their eggs and hatchlings including the nursery web spiders and the green lynx spider. Many parasitic wasps like the cicada killer, the great golden digger wasp and the tarantula hawk battle and paralyze insects and spiders to provision a nest for their young. Some predatory fireflies mimic the light flashing patterns of more docile species to entrap them for prey, and certain tropical cockroach males are female impersonators that trick more dominant males into mating and while the dominant male is in a compromising position, the female impersonator bites off its competitor’s wings, virtually emasculating him.

Why do you think so many people are so repelled by bugs, despite their obvious merits?

People are often repelled by things they don’t understand, which is one of the reasons humans are often such an intolerant society.

To us Brits, a bug is a germ, a microbe that causes an illness, could that be the subject of The Curious World of Bugs 2.0?

Not a chance. I am not interested in viewing the world through a microscope. Besides, germs are better left to scientists and not artists with an interest in pop culture like me.

Shrinking synchrotrons, stink bugs, odour vie

  • Shrinking synchrotrons – Details of a tabletop synchrotron device has been revealed by an international team of scientists in the journal Nature Physics. The new device could revolutionise X-ray work and preclude the need for large-scale synchrotrons in many structural studies without compromising resolution or atomic detail.
  • Kicking up a stink bug – Japanese researchers have used UV-Vis and nuclear magnetic resonance spectroscopy to help them develop a potential repellent for the invidious stink bug, an invasive pest species that has been spreading rapidly through the USA, invading homes and damaging crops.
  • Odour vie – Electron paramagnetic resonance spectroscopy has allowed researchers to study how nanoparticles can eliminate offensive household odours by removing the odour molecules at source rather than simply masking the bad smells.

Latest science snippets

  • Shampoo in your eyes – Botanical extracts added to shampoos almost never do anything at all and are usually  there purely and simply to make the product look more natural.   They are used at very low levels indeed. Expensive shampoo is a waste of money as is the cheap stuff you buy by the gallon. Supermarket own brands are fine, apparently.
  • Free scientific calculator – Red Crab is a free and portable calculator for Windows that is perfectly suitable for complex algebraic equations like fractions, square roots, exponents and a lot more. The best option to take a look at the calculator’s capabilities is to load a few of the demo projects that ship with the download.
  • First all-digital science textbook will be free – Within two and a half years, the E.O. Wilson Biodiversity Foundation hopes to complete a 59-chapter digital textbook about biology called Life on Earth. As each chapter is finished, the foundation plans to put it into the hands of anyone who wants it, for free.

Olive oil, breast cancer, gigapixel scans

  • Olive oil biophenols – Raman reveals all – The first report of Raman spectroscopy being used to look at chemical structures in olive oil has been published. The study establishes Raman as a rapid, non-destructive and reliable analytical technique for identifying bioactive components, such as biophenols in dietary extracts and surpasses other analytical methods.
  • One nanoparticle for targeting, tracking and treating breast cancer – Nanoparticles coupled to a fluorescent dye can be used to target tumour-specific molecules in breast cancer providing a way to track the particles by NIR spectroscopy, to enhance magnetic resonance imaging and to deliver an anticancer payload only to diseased cells.
  • Zoom and enhance for medical imaging – Computer scientists at the University of Utah have developed software that can generate rapid previews of super-high resolution images for medical, astronomical, and other applications. Images containing billions to hundreds of billions of pixels drain computer resources rapidly but a new technique for analysing the data could allow gigapixel MRI scans and other images to be previewed and manipulated much more easily and quickly than is currently possible.