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	<title>Comments on: Melamine and Kidney Failure</title>
	<atom:link href="http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/feed" rel="self" type="application/rss+xml" />
	<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html</link>
	<description>Science Blog from Freelance Science Writer David Bradley</description>
	<lastBuildDate>Thu, 09 Feb 2012 08:25:37 +0000</lastBuildDate>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-2#comment-654314</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Sat, 14 Jan 2012 16:20:39 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-654314</guid>
		<description>I&#039;d talk to your vet. As I understand it, there is the possible for kidney damage but it all depends on dose, your veterinarian would be able to best advise you if there is a problem with your pet.</description>
		<content:encoded><![CDATA[<p>I&#8217;d talk to your vet. As I understand it, there is the possible for kidney damage but it all depends on dose, your veterinarian would be able to best advise you if there is a problem with your pet.</p>
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		<title>By: carol</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-1#comment-654199</link>
		<dc:creator>carol</dc:creator>
		<pubDate>Sat, 14 Jan 2012 04:25:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-654199</guid>
		<description>Is there any cure or or treatment for animals that have eaten the tainted dog treats?</description>
		<content:encoded><![CDATA[<p>Is there any cure or or treatment for animals that have eaten the tainted dog treats?</p>
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		<title>By: tri</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-1#comment-560864</link>
		<dc:creator>tri</dc:creator>
		<pubDate>Wed, 15 Oct 2008 20:22:15 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-560864</guid>
		<description>Although the renal failure in infants could have been  due to the combined crystal formation of cyanuric acid and melamine,  The cyanuric acid isn&#039;t made kidneys.

In 2007 it was a contaminant in the pet food, along with melamine.

see Dobson&#039;s article:

http://toxsci.oxfordjournals.org/cgi/content/abstract/106/1/251

2 other labs also showed crystals form in animals given both melamine and cyanuric acid.

Puschner et al (cats):

http://www.ncbi.nlm.nih.gov/pubmed/17998549?ordinalpos=3&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Reimschuessel et al  (fish and pigs):

http://www.ncbi.nlm.nih.gov/pubmed/18764697?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

Older studies using only melamine did not find those crystals, but a long term study DID find kidney stones

Urinary bladder carcinogenesis induced by melamine in F344 male rats: correlation between carcinogenicity and urolith formation.

Ogasawara et al 1995  PMID: 7586198

Stones (obstruction) could cause acute renal failure in the babies if it is not diagnosed rapidly.  

It is possible BOTH of these scenarios are going on in the present adulteration event in China</description>
		<content:encoded><![CDATA[<p>Although the renal failure in infants could have been  due to the combined crystal formation of cyanuric acid and melamine,  The cyanuric acid isn&#8217;t made kidneys.</p>
<p>In 2007 it was a contaminant in the pet food, along with melamine.</p>
<p>see Dobson&#8217;s article:</p>
<p><a href="http://toxsci.oxfordjournals.org/cgi/content/abstract/106/1/251" rel="nofollow">http://toxsci.oxfordjournals.org/cgi/content/abstract/106/1/251</a></p>
<p>2 other labs also showed crystals form in animals given both melamine and cyanuric acid.</p>
<p>Puschner et al (cats):</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/17998549?ordinalpos=3&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/17998549?ordinalpos=3&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</a></p>
<p>Reimschuessel et al  (fish and pigs):</p>
<p><a href="http://www.ncbi.nlm.nih.gov/pubmed/18764697?ordinalpos=1&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum" rel="nofollow">http://www.ncbi.nlm.nih.gov/pubmed/18764697?ordinalpos=1&#038;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum</a></p>
<p>Older studies using only melamine did not find those crystals, but a long term study DID find kidney stones</p>
<p>Urinary bladder carcinogenesis induced by melamine in F344 male rats: correlation between carcinogenicity and urolith formation.</p>
<p>Ogasawara et al 1995  PMID: 7586198</p>
<p>Stones (obstruction) could cause acute renal failure in the babies if it is not diagnosed rapidly.  </p>
<p>It is possible BOTH of these scenarios are going on in the present adulteration event in China</p>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-1#comment-556313</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Fri, 10 Oct 2008 08:01:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-556313</guid>
		<description>A post on a Chinese blog linking back to Sciencebase had a comment mentioning that the bacterium for &lt;a href=&quot;http://en.wikipedia.org/wiki/Kawasaki_disease&quot; rel=&quot;nofollow&quot;&gt;Kawasaki syndrome&lt;/a&gt; had been found in contaminated powdered milk. This is very odd given that no one knows the causative agent of that syndrome although it is thought to be a superantigen rather than bacteria or virus. Anyone else seen mention of Kawasaki in the context of melamine contamination? And, purleez, no motorbike jokes...</description>
		<content:encoded><![CDATA[<p>A post on a Chinese blog linking back to Sciencebase had a comment mentioning that the bacterium for <a href="http://en.wikipedia.org/wiki/Kawasaki_disease" rel="nofollow">Kawasaki syndrome</a> had been found in contaminated powdered milk. This is very odd given that no one knows the causative agent of that syndrome although it is thought to be a superantigen rather than bacteria or virus. Anyone else seen mention of Kawasaki in the context of melamine contamination? And, purleez, no motorbike jokes&#8230;</p>
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	<item>
		<title>By: Share</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-1#comment-555407</link>
		<dc:creator>Share</dc:creator>
		<pubDate>Thu, 09 Oct 2008 04:37:52 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-555407</guid>
		<description>The passage concerning the FAO and agricultural fertlisers is very important. Thank you for informing!</description>
		<content:encoded><![CDATA[<p>The passage concerning the FAO and agricultural fertlisers is very important. Thank you for informing!</p>
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		<title>By: Andrew Sun</title>
		<link>http://www.sciencebase.com/science-blog/melamine-and-kidney-failure.html/comment-page-1#comment-554657</link>
		<dc:creator>Andrew Sun</dc:creator>
		<pubDate>Wed, 08 Oct 2008 09:38:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/?p=2354#comment-554657</guid>
		<description>Beijing is afraid of the total bankruptcy of the national milk industry so they have to save at least one. And they also don&#039;t like to see large scale civil lawsuits towards the milk industry but hope to pay and pacify the victims governmentally. These methods are tyrannical indeed but in China at least things must be so.</description>
		<content:encoded><![CDATA[<p>Beijing is afraid of the total bankruptcy of the national milk industry so they have to save at least one. And they also don&#8217;t like to see large scale civil lawsuits towards the milk industry but hope to pay and pacify the victims governmentally. These methods are tyrannical indeed but in China at least things must be so.</p>
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