Comments on: Ptaquiloside Redux http://www.sciencebase.com/science-blog/ptaquiloside-redux.html Science Blog from Freelance Science Writer David Bradley Sat, 07 Nov 2009 00:41:44 +0000 http://wordpress.org/?v=2.8.5 hourly 1 By: M J Brewer http://www.sciencebase.com/science-blog/ptaquiloside-redux.html/comment-page-1#comment-494485 M J Brewer Mon, 28 Jul 2008 11:33:56 +0000 http://www.sciencebase.com/science-blog/ptaquiloside-redux.html#comment-494485 We have recently had a few days holiday in the lake district in the Ambleside area taking our Springer Spaniel dog along with us. On her walks into the local area of the camp site and into the woods she occasionally had a chew at the bracken fern that was growing in abundance around where we stayed. On the final day of our holiday she suffered an epileptic fit but fortunately soon recovered. She is 7 years old and has never suffered from this problem before and on visiting the vet once we arrived home he was satisfied that she did not seem to have suffered any bad effects from the fit but could not say if the fern could have caused it. Could you please advise me as to whether the bracken fern that she ingested could have caused her to have a fit with the known toxins in the plant? Sincere regards M J Brewer We have recently had a few days holiday in the lake district in the Ambleside area taking our Springer Spaniel dog along with us.

On her walks into the local area of the camp site and into the woods she occasionally had a chew at the bracken fern that was growing in abundance around where we stayed. On the final day of our holiday she suffered an epileptic fit but fortunately soon recovered. She is 7 years old and has never suffered from this problem before and on visiting the vet once we arrived home he was satisfied that she did not seem to have suffered any bad effects from the fit but could not say if the fern could have caused it.

Could you please advise me as to whether the bracken fern that she ingested could have caused her to have a fit with the known toxins in the plant?

Sincere regards

M J Brewer

]]> By: Kiyoyuki Yamada http://www.sciencebase.com/science-blog/ptaquiloside-redux.html/comment-page-1#comment-194512 Kiyoyuki Yamada Thu, 15 Nov 2007 08:07:54 +0000 http://www.sciencebase.com/science-blog/ptaquiloside-redux.html#comment-194512 Via email: Dr. David Bradley, Science Writer Nearly ten years ago, you wrote an article on bracken toxin ptaquiloside, and at that time you were in communication with me by e-mail about this problem. During the past several years, there appeared reports as to veterinary medicine and ecology on ptaquiloside. Recently (August 2007) we published a review article including the above mentioned results: <a href="http://www.rsc.org/publishing/journals/NP/article.asp?doi=b614160a" rel="nofollow">Nat. Prod. Rep., 2007, 24, 798-813</a>. I am informing you of the appearance of our review, which may be helpful for your work. Best wishes, Kiyoyuki Yamada, Nagoya University Via email:

Dr. David Bradley, Science Writer

Nearly ten years ago, you wrote an article on bracken toxin ptaquiloside, and at that time you were in communication with me by e-mail about this problem. During the past several years, there appeared reports as to veterinary medicine and ecology on ptaquiloside. Recently (August 2007) we published a review article including the above mentioned results: Nat. Prod. Rep., 2007, 24, 798-813. I am informing you of the appearance of our review, which may be helpful for your work.

Best wishes,

Kiyoyuki Yamada, Nagoya University

]]> By: David Bradley http://www.sciencebase.com/science-blog/ptaquiloside-redux.html/comment-page-1#comment-153216 David Bradley Tue, 02 Oct 2007 14:21:35 +0000 http://www.sciencebase.com/science-blog/ptaquiloside-redux.html#comment-153216 David, so sorry to hear about your niece. I take it you saw my earlier article, which is rather out of date now - http://www.chm.bris.ac.uk/motm/ptq/ptqh.htm I don't have any additional information on the connection between bracken, ptaquiloside and cancer, but the latest research papers that mention both ptaquiloside and cancer can be found <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?term=ptaquiloside%20%20cancer&sourceid=mozilla-search&db=PubMed&orig_db=PubMed&dispmax=20&dopt=DocSum" rel="nofollow">here</a> db David, so sorry to hear about your niece. I take it you saw my earlier article, which is rather out of date now – http://www.chm.bris.ac.uk/motm/ptq/ptqh.htm

I don’t have any additional information on the connection between bracken, ptaquiloside and cancer, but the latest research papers that mention both ptaquiloside and cancer can be found here

db

]]> By: David Nolan http://www.sciencebase.com/science-blog/ptaquiloside-redux.html/comment-page-1#comment-153212 David Nolan Tue, 02 Oct 2007 13:57:47 +0000 http://www.sciencebase.com/science-blog/ptaquiloside-redux.html#comment-153212 Funny that I should come across this article after Google searching Ptaquiloside. I am trying to learn more about the compound and the bracken associated with it. My niece has developed stomach cancer at 31. It has metastasized and she has just begun chemotherapy. I believe that it is genetic since there is a family history but I did not want to make an assumption. She tested negative for H. pylori and is a nonsmoker/drinker. We both grew up in a dairy region of mid-Michigan and ate plenty of local beef and deer and drank lots of milk. I see lots of info on Venezuela, New Zealand and Japan about their cattle and bracken connection but so far, nothing about bracken in the US. I am going to do some more searching around but I would appreciate any information on Ptaquiloside, bracken and stomach cancer here in the States, specifically the Midwest, that anyone might have. Thanks for the update on the article and the research. Funny that I should come across this article after Google searching Ptaquiloside. I am trying to learn more about the compound and the bracken associated with it. My niece has developed stomach cancer at 31. It has metastasized and she has just begun chemotherapy. I believe that it is genetic since there is a family history but I did not want to make an assumption. She tested negative for H. pylori and is a nonsmoker/drinker. We both grew up in a dairy region of mid-Michigan and ate plenty of local beef and deer and drank lots of milk. I see lots of info on Venezuela, New Zealand and Japan about their cattle and bracken connection but so far, nothing about bracken in the US. I am going to do some more searching around but I would appreciate any information on Ptaquiloside, bracken and stomach cancer here in the States, specifically the Midwest, that anyone might have. Thanks for the update on the article and the research.

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