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	<title>Comments on: Viruses Versus Bacteria</title>
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	<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html</link>
	<description>Science Blog from Freelance Science Writer David Bradley</description>
	<lastBuildDate>Thu, 09 Feb 2012 08:25:37 +0000</lastBuildDate>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-4#comment-637081</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Mon, 31 May 2010 18:51:39 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-637081</guid>
		<description>That&#039;s better. I don&#039;t mind approving a comment that actually adds something new to the blogosphere. Just don&#039;t want to approve stuff that&#039;s been cut and paste on other sites. Thanks for contributing. It&#039;s appreciated (now).</description>
		<content:encoded><![CDATA[<p>That&#8217;s better. I don&#8217;t mind approving a comment that actually adds something new to the blogosphere. Just don&#8217;t want to approve stuff that&#8217;s been cut and paste on other sites. Thanks for contributing. It&#8217;s appreciated (now).</p>
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		<title>By: perfectmus</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-4#comment-637077</link>
		<dc:creator>perfectmus</dc:creator>
		<pubDate>Mon, 31 May 2010 16:24:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-637077</guid>
		<description>With all due respect it has everthing to do with what is discussed:

“Why are we so worried about outbreaks of E coli, salmonella, and other bacteria. Surely, we have a whole armoury of trusty phages to turn to that can wipe out the rank and file of resistance microbes quickly? Well, we don’t, somewhere between the discovery of penicillin and the second world war, chemical antibiotics fell in to pharmaceutical line as the treatment of choice to deal with bacterial infections. Never mind the fact that within months of the first dose of penicillin being given doctors were already seeing resistance. Today, there are thousands of antibiotics on the market, some are even available over-the-counter in southern Europe. Moreover, in countries that cannot really afford to use them, individuals receive short dose regimens that don’t cure their illness and provide new opportunities for bacteria to develop resistant genes.”

As the article points out, there is a viral and bacterial problem.  

The fact is that silver has been found to be very antiviral and antibacterial.
Text Book of Materia Medica and Their Therapeutics by A.S Blumgarten, 6th Edition, M.D., F.A.C.P. printed by The McMillan Company in New York. 1935, the first Edition was written in 1914, points out that silver is to be used to treat infections caused by bacteria.

Rarely are books found that contain references to silver, I happen to have one that dates back to 1914.

Aside from the fact that research has proven that silver can kill HIV:  http://www.jnanobiotechnology.com/content/8/1/1
http://www.sciencedaily.com/releases/2010/05/100524101339.htm

My point is if Nano Particle have shown positive results, Silver Atoms due to their size will produces even better results.

This article pointed out a problem, I simply pointed out a solution to a problem.</description>
		<content:encoded><![CDATA[<p>With all due respect it has everthing to do with what is discussed:</p>
<p>“Why are we so worried about outbreaks of E coli, salmonella, and other bacteria. Surely, we have a whole armoury of trusty phages to turn to that can wipe out the rank and file of resistance microbes quickly? Well, we don’t, somewhere between the discovery of penicillin and the second world war, chemical antibiotics fell in to pharmaceutical line as the treatment of choice to deal with bacterial infections. Never mind the fact that within months of the first dose of penicillin being given doctors were already seeing resistance. Today, there are thousands of antibiotics on the market, some are even available over-the-counter in southern Europe. Moreover, in countries that cannot really afford to use them, individuals receive short dose regimens that don’t cure their illness and provide new opportunities for bacteria to develop resistant genes.”</p>
<p>As the article points out, there is a viral and bacterial problem.  </p>
<p>The fact is that silver has been found to be very antiviral and antibacterial.<br />
Text Book of Materia Medica and Their Therapeutics by A.S Blumgarten, 6th Edition, M.D., F.A.C.P. printed by The McMillan Company in New York. 1935, the first Edition was written in 1914, points out that silver is to be used to treat infections caused by bacteria.</p>
<p>Rarely are books found that contain references to silver, I happen to have one that dates back to 1914.</p>
<p>Aside from the fact that research has proven that silver can kill HIV:  <a href="http://www.jnanobiotechnology.com/content/8/1/1" rel="nofollow">http://www.jnanobiotechnology.com/content/8/1/1</a><br />
<a href="http://www.sciencedaily.com/releases/2010/05/100524101339.htm" rel="nofollow">http://www.sciencedaily.com/releases/2010/05/100524101339.htm</a></p>
<p>My point is if Nano Particle have shown positive results, Silver Atoms due to their size will produces even better results.</p>
<p>This article pointed out a problem, I simply pointed out a solution to a problem.</p>
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		<title>By: perfectmus</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-4#comment-637058</link>
		<dc:creator>perfectmus</dc:creator>
		<pubDate>Thu, 27 May 2010 14:54:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-637058</guid>
		<description>It would be great if studies could be done by testing colloidal silver atoms on viruses and bacteria.

For years now people have sworn by colloidal silver, however  the 50 year old method of making colloidal silver only produces nano particles which happen to be 29 atoms clumped together to make a single cluster or particle. 

To make colloidal silver nano particles requires the use of dangerous chemicals, and the typical colloidal silver has been found to have adverse effects if too much is taken in.
Now that there is a modern method of making colloidal silver atoms, I think it would be great if someone “picked up the mantle” and test them since this product is not made with chemicals, has a higher PPM than the Nano Particle production method, and the particles are of the size of an atom.

Since silver has been proven to be anti viral and anti bacterial, it only makes sense to test and see what colloidal silver atoms will do to enhance the quality of life.</description>
		<content:encoded><![CDATA[<p>It would be great if studies could be done by testing colloidal silver atoms on viruses and bacteria.</p>
<p>For years now people have sworn by colloidal silver, however  the 50 year old method of making colloidal silver only produces nano particles which happen to be 29 atoms clumped together to make a single cluster or particle. </p>
<p>To make colloidal silver nano particles requires the use of dangerous chemicals, and the typical colloidal silver has been found to have adverse effects if too much is taken in.<br />
Now that there is a modern method of making colloidal silver atoms, I think it would be great if someone “picked up the mantle” and test them since this product is not made with chemicals, has a higher PPM than the Nano Particle production method, and the particles are of the size of an atom.</p>
<p>Since silver has been proven to be anti viral and anti bacterial, it only makes sense to test and see what colloidal silver atoms will do to enhance the quality of life.</p>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-3#comment-475549</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Thu, 03 Jul 2008 08:21:46 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-475549</guid>
		<description>Congratulations to Sciencebase regular Grace Filby who recently received an award for her work on understanding and promoting bacteriophages:

&quot;A researcher’s work on the health value of bacteriophages has been rewarded with a Churchill Fellows Silver Medallion. Grace Filby, of Reigate, Surrey, travelled to Canada, Georgia, Poland and USA last year to see the application of phages in hospitals and clinics and explore the potential for 21st century medicine. Their ability to kill bacteria was first reported during the First World War. They started to be used as a treatment for infections before antibiotics became widely available. Her journeys were funded by the Winston Churchill Memorial Trust, which offers grants to British citizens for travel-related projects that benefit society. The Trust, in June, recognised Filby&#039;s work by awarding her the Churchill Fellows Silver Medallion.</description>
		<content:encoded><![CDATA[<p>Congratulations to Sciencebase regular Grace Filby who recently received an award for her work on understanding and promoting bacteriophages:</p>
<p>&#8220;A researcher’s work on the health value of bacteriophages has been rewarded with a Churchill Fellows Silver Medallion. Grace Filby, of Reigate, Surrey, travelled to Canada, Georgia, Poland and USA last year to see the application of phages in hospitals and clinics and explore the potential for 21st century medicine. Their ability to kill bacteria was first reported during the First World War. They started to be used as a treatment for infections before antibiotics became widely available. Her journeys were funded by the Winston Churchill Memorial Trust, which offers grants to British citizens for travel-related projects that benefit society. The Trust, in June, recognised Filby&#8217;s work by awarding her the Churchill Fellows Silver Medallion.</p>
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		<title>By: Grace</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-3#comment-177926</link>
		<dc:creator>Grace</dc:creator>
		<pubDate>Tue, 06 Nov 2007 12:58:43 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-177926</guid>
		<description>It may also be of interest to read the following from the Polish Academy of Sciences where I met patients who had already been treated with phages for MRSA bone infections. The website states: 

&quot;The indications of the range of phage therapy are as follows: septicemia, regardless of their origin, postoperative infections, mucopurulent bronchitis, asthma, pneumonia, pleuritis, furunculosis, otitis media, sinusitis, meningitis, acute lymphangitis, abscesses cutis and decubitus ulcer, pyogenic arthritis, myositis, osteomyelitis, suppurative infections after injuries of soft tissue, such as contusions, burns, pyogenic infection after bone fractures, and chronic infections of the urinary tract.&quot; 

The reference is  http://www.iitd.pan.wroc.pl/phages/phages.html 

Medical opinion from Prof. Bill V. Way, a dermatologist in the USA agrees with me that some of these would be very deep infections, not just shallow infections. The Polish scientists state categorically that more than 80% of patients were cured, and that detailed information can be obtained from Prof. Andrzej Gorski and Dr. Beata Weber-Dabrowska, e-mail: agorski@ikp.pl.

It will be interesting to hear the final result of the Phase 2 UK clinical trial nearing completion -

&quot;Prof. Tony Wright: Pseudomonas is one of the very, very common problems we have with ear disease and discharge. Often unpleasant colour, can be very smelly, and I&#039;ve seen patients as part of the trial who&#039;ve had infections for twenty years. On and off, but more on than off.&quot; In some instances there can be ulceration, mucopurulent discharge, and possible progression to very severe otitis externa, and in some very rare cases, even death.</description>
		<content:encoded><![CDATA[<p>It may also be of interest to read the following from the Polish Academy of Sciences where I met patients who had already been treated with phages for MRSA bone infections. The website states: </p>
<p>&#8220;The indications of the range of phage therapy are as follows: septicemia, regardless of their origin, postoperative infections, mucopurulent bronchitis, asthma, pneumonia, pleuritis, furunculosis, otitis media, sinusitis, meningitis, acute lymphangitis, abscesses cutis and decubitus ulcer, pyogenic arthritis, myositis, osteomyelitis, suppurative infections after injuries of soft tissue, such as contusions, burns, pyogenic infection after bone fractures, and chronic infections of the urinary tract.&#8221; </p>
<p>The reference is  <a href="http://www.iitd.pan.wroc.pl/phages/phages.html" rel="nofollow">http://www.iitd.pan.wroc.pl/phages/phages.html</a> </p>
<p>Medical opinion from Prof. Bill V. Way, a dermatologist in the USA agrees with me that some of these would be very deep infections, not just shallow infections. The Polish scientists state categorically that more than 80% of patients were cured, and that detailed information can be obtained from Prof. Andrzej Gorski and Dr. Beata Weber-Dabrowska, e-mail: <a href="mailto:agorski@ikp.pl">agorski@ikp.pl</a>.</p>
<p>It will be interesting to hear the final result of the Phase 2 UK clinical trial nearing completion -</p>
<p>&#8220;Prof. Tony Wright: Pseudomonas is one of the very, very common problems we have with ear disease and discharge. Often unpleasant colour, can be very smelly, and I&#8217;ve seen patients as part of the trial who&#8217;ve had infections for twenty years. On and off, but more on than off.&#8221; In some instances there can be ulceration, mucopurulent discharge, and possible progression to very severe otitis externa, and in some very rare cases, even death.</p>
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		<title>By: Grace</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-3#comment-177014</link>
		<dc:creator>Grace</dc:creator>
		<pubDate>Mon, 05 Nov 2007 10:02:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-177014</guid>
		<description>Please may I bring some specific research to your attention? It is explained in my Winston Churchill Report, as I mentioned. 

Please refer to page 5 regarding peritonitis: &quot;The message is that phages could be applied therapeutically as prevention or rescue work, directly through the lymphatic system - without even having to go through the blood system. Indeed, the experiments with animals and case reports of human patients indicate that it works very quickly and efficiently. &quot; This is from research in Georgia.

Then on pages 10 and 11, you will find some exciting news about novel applications of bacteriophages.  For example, regarding Alzheimer&#039;s, &quot;Administered through the nose, the phages can reach the brain directly and rapidly. Her (Prof. Beka Solomon, Israel)  team&#039;s research with mice demonstrates that phages can reduce the extracellular plaque and also brain inflammation without adverse effects. This may open the way for various new treatments of other neurological diseases including Parkinson&#039;s Disease and Huntingdon&#039;s Disease.&quot;

You will also see that there is some recent Polish research (all published in English) &quot;uniquely based on some inspiring observations that pieces of lung tissue bathed in HAP1 phages (lovely name!) had significantly less melanoma. The effect is clearly visible in photographs. The scientists state that the effect of phages is immunological. The research publications prove that, under well-defined circumstances, phages can have anti-metastatic activity (anti-cancer/anti-tumour).&quot; 

There is more news from Poland about anti-inflammatory diseases of the bowel and renal function. There is also the possibility of new therapeutic treatments or preventatives for a range of viral infections such as adenoviruses and the Herpes virus.

The other novel application that I am referring to in my report is that &quot;research indicates that phages could help in treating oral bacterial infection and biofilm too&quot;. There is a great deal of research and comment on this from the USA and the UK.

As I understand it, bacteriophages do only &#039;infect&#039; and destroy bacteria - but now it is becoming clear that they have other beneficial functions too in the body, that we were not aware of when they were first discovered and named 90 years ago. Perhaps this would explain some misunderstanding in the past in the role of bacteriophages regarding oncological and immunological interactions. 

So I stand by my comment: &quot;They are certainly versatile little organisms, whose value has been vastly underrated so far.&quot;  Hope that helps with the discussion. 

I would like to add that there is very strong evidence for phage safety, and also some very useful evidence that it is much cheaper than antibiotics for the treatment of staphylococcal infections - &#039;about half the cost of 10-day therapy with vancomycin and several times less compared with the other drugs&#039;  (Miedzybrodzki R et al, 2007.
 http://www.relax-well.co.uk/less_expensive_than_antibiotics.pdf )

The web addresses for the report are www.relax-well.co.uk and www.amazingphage.info (with photo galleries, a blog, recorded interviews with scientists and clinicians, etc.)

Many thanks. I hope you can help by letting people know.</description>
		<content:encoded><![CDATA[<p>Please may I bring some specific research to your attention? It is explained in my Winston Churchill Report, as I mentioned. </p>
<p>Please refer to page 5 regarding peritonitis: &#8220;The message is that phages could be applied therapeutically as prevention or rescue work, directly through the lymphatic system &#8211; without even having to go through the blood system. Indeed, the experiments with animals and case reports of human patients indicate that it works very quickly and efficiently. &#8221; This is from research in Georgia.</p>
<p>Then on pages 10 and 11, you will find some exciting news about novel applications of bacteriophages.  For example, regarding Alzheimer&#8217;s, &#8220;Administered through the nose, the phages can reach the brain directly and rapidly. Her (Prof. Beka Solomon, Israel)  team&#8217;s research with mice demonstrates that phages can reduce the extracellular plaque and also brain inflammation without adverse effects. This may open the way for various new treatments of other neurological diseases including Parkinson&#8217;s Disease and Huntingdon&#8217;s Disease.&#8221;</p>
<p>You will also see that there is some recent Polish research (all published in English) &#8220;uniquely based on some inspiring observations that pieces of lung tissue bathed in HAP1 phages (lovely name!) had significantly less melanoma. The effect is clearly visible in photographs. The scientists state that the effect of phages is immunological. The research publications prove that, under well-defined circumstances, phages can have anti-metastatic activity (anti-cancer/anti-tumour).&#8221; </p>
<p>There is more news from Poland about anti-inflammatory diseases of the bowel and renal function. There is also the possibility of new therapeutic treatments or preventatives for a range of viral infections such as adenoviruses and the Herpes virus.</p>
<p>The other novel application that I am referring to in my report is that &#8220;research indicates that phages could help in treating oral bacterial infection and biofilm too&#8221;. There is a great deal of research and comment on this from the USA and the UK.</p>
<p>As I understand it, bacteriophages do only &#8216;infect&#8217; and destroy bacteria &#8211; but now it is becoming clear that they have other beneficial functions too in the body, that we were not aware of when they were first discovered and named 90 years ago. Perhaps this would explain some misunderstanding in the past in the role of bacteriophages regarding oncological and immunological interactions. </p>
<p>So I stand by my comment: &#8220;They are certainly versatile little organisms, whose value has been vastly underrated so far.&#8221;  Hope that helps with the discussion. </p>
<p>I would like to add that there is very strong evidence for phage safety, and also some very useful evidence that it is much cheaper than antibiotics for the treatment of staphylococcal infections &#8211; &#8216;about half the cost of 10-day therapy with vancomycin and several times less compared with the other drugs&#8217;  (Miedzybrodzki R et al, 2007.<br />
 <a href="http://www.relax-well.co.uk/less_expensive_than_antibiotics.pdf" rel="nofollow">http://www.relax-well.co.uk/less_expensive_than_antibiotics.pdf</a> )</p>
<p>The web addresses for the report are <a href="http://www.relax-well.co.uk" rel="nofollow">http://www.relax-well.co.uk</a> and <a href="http://www.amazingphage.info" rel="nofollow">http://www.amazingphage.info</a> (with photo galleries, a blog, recorded interviews with scientists and clinicians, etc.)</p>
<p>Many thanks. I hope you can help by letting people know.</p>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-3#comment-176959</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Mon, 05 Nov 2007 08:04:45 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-176959</guid>
		<description>Thanks for your input Michael. As I understand it from Häusler&#039;s book, that lack of antibiotics is not the only reason that Russian medics turned to bacteriophages. However, it does seem from the various case studies that shallow infections are most susceptible to bacteriophages while attacking an &quot;internal&quot; bacterial infection is a totally different matter. That isn&#039;t to say that scientists shouldn&#039;t continue to investigate antibacterial activity and putative anticancer activity. As we all know, there are no panaceas, just additional imperfect weapons in our battle against pathogens.</description>
		<content:encoded><![CDATA[<p>Thanks for your input Michael. As I understand it from Häusler&#8217;s book, that lack of antibiotics is not the only reason that Russian medics turned to bacteriophages. However, it does seem from the various case studies that shallow infections are most susceptible to bacteriophages while attacking an &#8220;internal&#8221; bacterial infection is a totally different matter. That isn&#8217;t to say that scientists shouldn&#8217;t continue to investigate antibacterial activity and putative anticancer activity. As we all know, there are no panaceas, just additional imperfect weapons in our battle against pathogens.</p>
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		<title>By: michael</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-3#comment-176632</link>
		<dc:creator>michael</dc:creator>
		<pubDate>Mon, 05 Nov 2007 01:12:21 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-176632</guid>
		<description>From looking at all the comments I think you all have a very inaccurate understanding of what bacteriophages are.  They are viruses that only infect bacteria.  They are incapable of infecting cancer cells or other cells for that matter.  Bacteriophages are attacked by immune cells and destroyed easily inside the body.  Phage therapy is limited to shallow infections and cannot be used to treat internal infections.  Antibiotics were used in the west because they treated internal infections very well while the east [USSR especially] were forced to use phage therapy because of the lack of antibiotics available.  Until we find a way to alter bacteriophages to the point where our immune system doesn&#039;t attack them outright, the treatment can only be used on shallow infections and nothing more.  Cancer is being treated by certain genetically modified viruses, they are just nothing like bacteriophages by any means.  They are as related to bacteriophages as we are to house cats.</description>
		<content:encoded><![CDATA[<p>From looking at all the comments I think you all have a very inaccurate understanding of what bacteriophages are.  They are viruses that only infect bacteria.  They are incapable of infecting cancer cells or other cells for that matter.  Bacteriophages are attacked by immune cells and destroyed easily inside the body.  Phage therapy is limited to shallow infections and cannot be used to treat internal infections.  Antibiotics were used in the west because they treated internal infections very well while the east [USSR especially] were forced to use phage therapy because of the lack of antibiotics available.  Until we find a way to alter bacteriophages to the point where our immune system doesn&#8217;t attack them outright, the treatment can only be used on shallow infections and nothing more.  Cancer is being treated by certain genetically modified viruses, they are just nothing like bacteriophages by any means.  They are as related to bacteriophages as we are to house cats.</p>
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		<title>By: David Bradley</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-2#comment-156430</link>
		<dc:creator>David Bradley</dc:creator>
		<pubDate>Thu, 11 Oct 2007 09:45:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-156430</guid>
		<description>Thanks for the update Grace, I&#039;ve removed the period from the second link as a bug/feature in Wordpress means those little dots get incorporated into the URL.

db</description>
		<content:encoded><![CDATA[<p>Thanks for the update Grace, I&#8217;ve removed the period from the second link as a bug/feature in WordPress means those little dots get incorporated into the URL.</p>
<p>db</p>
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		<title>By: Grace</title>
		<link>http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html/comment-page-2#comment-156424</link>
		<dc:creator>Grace</dc:creator>
		<pubDate>Thu, 11 Oct 2007 09:30:02 +0000</pubDate>
		<guid isPermaLink="false">http://www.sciencebase.com/science-blog/viruses-versus-bacteria.html#comment-156424</guid>
		<description>I wondered if you would like to read my Churchill Fellowship Report...

Please download it from the news page of www.relax-well.co.uk or from www.amazingphage.info</description>
		<content:encoded><![CDATA[<p>I wondered if you would like to read my Churchill Fellowship Report&#8230;</p>
<p>Please download it from the news page of <a href="http://www.relax-well.co.uk" rel="nofollow">http://www.relax-well.co.uk</a> or from <a href="http://www.amazingphage.info" rel="nofollow">http://www.amazingphage.info</a></p>
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