Intermittent fasting and life

The BBC showed a Horizon program recently in which it extolled the benefits of the so-called 5:2 diet, the on-off, alternating fasting diet. Apparently, scientists are “uncovering evidence that short periods of fasting, if properly controlled, could achieve a number of health benefits”. The show was presented as these often are by TV doctor Michael Mosley and as is often the case, he tested the diet on himself.

BBC News – The power of intermittent fasting.

In the close of an article about the show, Mosley says: “I was closely monitored throughout and found the 5:2 surprisingly easy. I will almost certainly continue doing it, albeit less often. Fasting, like eating, is best done in moderation.”

So, despite apparently being rather convinced, it appears that he’s not actually going to persist with it…

Anyway, that’s not my biggest problem with this kind of TV. One thing that always worries me about these kinds of programs, is that the presenter puts him or herself into the position of experimental subject. I don’t think you can be both experimenter and the experiment yourself in this kind of research. You need lots of people and controls (people who don’t get the intervention) so you can randomize who does and doesn’t take part and see what effect it has. If it’s just you, then there no one to compare your results with.

Moreover, in the Mosley 5:2 example, hasn’t he done lots of exercise and dietary modifications previously for other TV programs? He enthused about a short-burst exercise regime a while back too, although the actual metrics on his health didn’t really show much of an improvement at all. Apparently, on the 5:2 he did lose weight, but how are we to know that’s not down to his previous exercise and dietary regimes?

I have a friend who is trying the 5:2, he’s not lost any weight yet, but thinks it might be a good thing to be doing, which is fine. If he feels healthier because of it and is happy, then perhaps it doesn’t do any harm. If he loses a few pounds in the course of the diet then that’s great too, but he needs to watch out for metabolic bounce back. If he stops the 5:2 he might find his hunger levels have risen from what they were before and he ends up eating more on average than he did. This seems to be an inherent risk in low-calorie or calorie-restricted dieting. That said, there was some evidence published earlier this year that hinted the yo-yo effect of dieting may not be as hazardous as was once thought.

It’s very hard to know about dieting and life expectancy. After all, the final data doesn’t come until you’re dead by which point it’s too late. It seems, however, that over-indulgence and excess calories makes people heavier and being heavier puts extra physical strain on your heart, blood vessels, kidneys etc. Excess sugar can affect the functioning of your pancreas leading to diabetes which then damages your tissues. Fats and cholesterol can form layers of waxy gunk inside your organs and arteries and lead to blockages that increase the risk of heart attack and stroke.

But, there are overweight people who never develop cardiovascular disease or type 2 diabetes, live long and prosper and there are skinny marathon runners who need bypass surgery in middle age and die prematurely.

Despite what the lifestyle magazines and those selling diet and exercise self-help books say, we really don’t know what is truly good and bad for us. It’s not likely to turn out that pounds of lard and plenty of cigarettes will ever prove to be a good thing (although nicotine seems to reduce the risk of Parkinson’s disease). There are even disadvantages to eating a lot of fresh fruit in terms of rotting your teeth and giving you gut rot and indigestion. Dental and gum infection has been linked to heart disease while chronic digestive problems for some people might not only cause discomfort but may turn out to be a risk for esophagal and colon cancer. Who knows? The evidence can swing both ways.

The flaming sulfurous monster of the deep

UPDATE: Nothing new under the sun. Woehler himself described this reaction back in the 19th century. As a pyrotechnic snake firework it is of course banned because it’s highly toxic. An explanation in an old ACS paper for what’s going on thanks to Stuart Cantrill.

Ever burned mercury(II) thiocyanate powder in a fish tank? This has to be the most skin-crawliest, creepy chemical decomposition reaction. Always knew the alchemists were on to something with their brews of mercury, sulfur and urine…well maybe not the urine…

Thanks to Chemistry World Features Editor Neil Withers for highlighting.

Tracking with a purpose

The Human Face of Big Data app for iOS and Android will anonymously track your behaviour and help scientists crowdsource a big picture of humanity over the coming days.

The free app launches later today and will learn not only about yourself but also how you compare to others. You can compare answers about your family, trust, sleep, sex, dating, and dreams with millions of others around the world and even identify your Data Doppelganger.

You can map your daily footprint, share what brings you luck, and get a glimpse into the one thing people want to experience during their lifetime.

The Human Face of Big Data.

The moral dilemma

According to evolutionary anthropologist Christopher Boehm, “our moral sense is a sophisticated defence mechanism that enables individuals to survive and thrive in groups. One of the biggest risks of group living is the possibility of being punished for our misdeeds by those around us. Bullies, thieves, free-riders, and especially psychopaths are the most likely to suffer this fate. Getting by requires getting along, and this social type of selection, Boehm shows, singles out altruists for survival.”

It makes sense. In a recent “debate” between Britain’s Chief Rabbi, Lord Sacks and biologist Richard Dawkins, the origins of our moral compass were discussed. Dawkins, I imagine would agree with Boehm and he suggested that in a post-religious world, communities would decide on what is moral, he pointed out that this is already happening and the morals of even the 1960s, are very different from those of the 1860s and certainly shifted from our current “Western” morals. Sacks responded by saying that the true origin is God and yet then went on to say how community with 3500 years of history had settled on the morals and that those same morals would apply even if you didn’t believe in God.

Bottom line, evolutionarily we’re moral because it benefits us in terms of procreation. Belief in God is probably just an accident.

Skeptic » eSkeptic » Wednesday, September 26th, 2012.

The perfect app for vampires

The Transylvania branch of the National Health Service has just launched a free app for iOS and Android devices that lets vampires target willing victims easier than ever before without all that late-night stalking and morphing into bats malarkey.

The app lets victims donors search for a blood donor sessions and once they have found a convenient session can secure an appointment with the undead through the National Contact Centre. Once they’ve been relieved of their proverbial armful they can share their bloody activities on Facebook and Twitter.

Route guidance is provided through Google maps although for iPhone5 users, on reflection (if you still have one), you may want to get hold of an old-fashioned “A-to-Z” just in case you end up in some strange castle confronted by a talk, dark stranger with a widow’s peak and an endless supply of tooth whitener.

Give Blood.

The next SARS? Coronavirus case in UK

The UK alerted the World Health Organisation on Saturday to a case of acute respiratory syndrome with renal failure in a 49-year old man who had visited Saudi Arabia and Qatar. The man, a previously healthy, Qatari national, first showed symptoms on 3 September 2012 and was admitted to intensive care in Doha, Qatar on 7th. He was transferred by air ambulance to the UK on 11th where the Health Protection Agency confirmed infection with a previously unknown coronavirus.

According to Global News, there have been two other confirmed cases resulting in two deaths.

Coronaviruses infect the upper airways and gastrointestinal tract of mammals and birds. There are four to five strains known to infect humans and most are thought to simply cause a “common cold”. However, one coronavirus, SARS-CoV, led to a worldwide outbreak of severe acute respiratory syndrome (SARS) because it unusually affects both upper and lower respiratory tract infections as well as causing gastroenteritis.

SOURCES: WHO | Novel Coronavirus infection in the United Kingdom

Coronavirus – Wikipedia

Pearls of wisdom

UPDATE: Another 5-star review just in: “Bradley has certainly got a style that gets you in from the start. Erudite, yet inviting. It’s as if a bloody clever friend is telling you stuff that you kind of suspected, but for the prevalence of urban myth, pseudoscience and old wives tales, made you a little unsure unless you are an expert, a scientist or a know-it-all.

Bradley sets the records straight with a sense of humour and well founded knowledge that makes it a pleasure to read, as you become less ill-informed and happily equipped for a “and did you know” session at the next gathering of those that haven’t read his book.

I cannot wait for the release of the full volume, so I can pass my time in the loo and my evening mind-feeding with a mental smile and a contented feeling of being just a bit more well informed than earlier that day.”

John Emsley had this to say: ‘At last, a book that blows away many of the urban myths that we’ve come to accept without questioning. Well written and engrossing.’

Various people have been leaving a trail of pearls regarding my book Deceived Wisdom. You can get a the book here or if you’re in the UK order the hardback edition in plenty of time for Christmas.

Francis Wheen – Judging by the sampler, it’s my dream book. I may well have to order multiple copies as Christmas presents.

Jane de Lartigue – Awesome! Going on my Christmas wish list!

Milly B – Cool! I want some print copies for stocking fillers

MeKe – I will definitely encourage everyone to read your new book Deceived Wisdom

Sandy Dechert – A wicked and educated science hoot. Downloaded your summary, can’t wait for the book!

Crickett Cook – Call me old fashioned – nothing like the smell of a new book, in hand. Can’t wait!

Caroline Cross – Enjoyed the sampler, but are we deceived about snow flakes or not?

Amazon review – Ah, all those snippets of wisdom that we grow up with – information absorbed from your mother, father, granny, school teachers and that fount of all knowledge, `I read somewhere that.’ This is information so fundamental that it’s on the `everybody knows that…’ curriculum, but what if it’s actually wrong?

David Bradley, a top science writer based in the UK puts a plethora of common misconceptions under his microscope and shows you why the stuff that you thought was right is really rubbish.

Written with a light and humorous touch, reading `Deceived Wisdom’ will enable you to shoot down dinner-party bores, win endless quiz shows when Stephen Fry invites you to star in `QI’ and generally educate yourself beyond the misinformation doled out in primary and secondary schools (and probably quite a few universities).

I’ve just read the extended sampler, but will definitely get the full book when it’s released in November – it’ll be a great stocking filler for Xmas. It’s science, it’s information, but it’s fun!

Judy Stone – I enjoyed it!

Notes for a Periodic Table of Elements Songs

Working on creating a Periodic Table of the Elements in which each entry is a song:

Love is Like Oxygen – The Sweet
Gold – Spandau Ballet
Helium – Feeder
Titanium – David Guetta

Pocket full of Kryptonite?” http://t.co/dMtlfLFu

Radiohead ‘My Iron Lung’?

Lithium – Nirvana, Iron Man – Black Sabbath, Boron Under A Bad Sign – Cream

Kraftwerk – Uranium, Titanium and Neon Lights all songs :-)

Maxwell’s Silver Hammer, Iron Lung, Mercury (Bloc Party), Titanium (David Guetta)

Pencil Full of Lead – Paolo Nutini (even if inaccurate)?

Tin Soldier – Small Faces, Silver Machine – Hawkwind

“Copper” by Shellac? youtube.com/watch?v=H22upa…

“Einsten on a Beach” by Counting Crows for Einsteinium. Closest we’re gonna get: youtu.be/fND8kuZlvKs

When You Ar(e )Gon(e) – Avril Lavigne, Neon Lights – OMD, Oxygen – Spice Girls, Mercury – Counting Crows

Arcade Fire, “Neon Bible.” You get a whole album for periodic table, done by an Aristotelian element.

Oxygen by JJ72…easy one!

Iodine been waiting for a girl like you? #periodictablesongs
4:23 PM, Feb 7th via Twitter for iPhone

Carbon, carbon, carbon chameleon

Neon Tiger – The Killers

Platinum Blond by Paris Hilton!

Oxygene by Jean-Michell Jarre

“Palladium Nights” Ray Barretto, “The Chlorine Vendor” Ed Kuepper, “Tin Machine” Tin Machine, “Antimony” Robert Miles, “Float In An Iridium Sea” Noisettes, “Barium Springs” New Radical Storm Kings.

George Clinton’s Parliament “Osmium”

Mercury – Counting Crows

Sulfur – Slipknot

John Fowler – The Iodine Song
Dysprosium is a 5-piece melodic metal band based in the inner-eastern suburbs of Melbourne

Rhodium Records released an album by a band called Angry Chiwawah

There were many others…thanks to twitter and Facebook friends!

Faecal matters

One of the most trivial ethical debates raged on my Facebook page after I posted about whether one should hang a toilet roll “over” or “under”. Of course, for those with a vertical toilet roll holder, it’s a moot point. But, silliness aside, there is an important moral debate to be had in the context of the environment and global sustainability surrounding what we do with human waste – urine and faeces.

Each of us produces around a litre of urine each day (estimates of the range from person to person across the globe say 500 to 1500 ml) and several hundred grams of faeces (minimum estimated at 50 grams with some people producing half a kilo). The liquid can be treated relatively easily in situ – and used as grey water for flushing. Solid waste is a different matter but in many parts of the world separator and composting toilets are becoming common place. Civil engineer Nityanand Singh Maurya of the National Institute of Technology Patna, in Bihar, India, recently suggested that we should certainly not view human excreta as waste to be processed and disposed. Despite our queasiness about the potential for spreading disease and the risk of accumulating heavy metals in the food chain if human faeces are used as crop fertiliser, there are ways to get around the problems

India and China have long used human waste as fertiliser and soil conditioner, it is after all mostly carbon, nitrogen and phosphorus, chemically speaking. But, in “the West”, we expend vast quantities of clean water to flush away our waste and yet more water to process it so that it can be dumped, as it were. There is great potential for the use of domestic eco-sanitation, particularly in rural areas and given the high-energy content of human faeces, conversion to biomass for power production is also a serious option.

Maurya suggests that for rural areas in the developing world, urine-diverting toilets make it relatively easy to collect urine separately and allow faeces to be composted. In urban environments, urine can again be collected separately and used as grey water while anaerobic treatment of faeces at the local level allows it to be used for fertiliser or biomass, or biogas for that matter. These approaches reduce demands on water supply and processing.

Research Blogging IconSingh Maurya, N., (2012). Is human excreta a waste?, Int. J. Environmental Technology and Management, 15 (3-6) 332. DOI:

Photo by thejbird

Research Blogging IconMaurya, N.S. (2012). Is human excreta a waste?, International Journal of Environmental Technology and Management, 15 (3/4/5/6) DOI: 10.1504/IJETM.2012.049231

Toilet paper orientation

Whoever said Wikipedia, or Sciencebase come to that, was trivial? This is meaning-of-life stuff: Toilet paper when used with a toilet roll holder with a horizontal axle parallel to the wall has two possible orientations: the toilet paper may hang over (in front of) or under (behind) the roll. The choice is largely a matter of personal preference, dictated by habit.

via Toilet paper orientation – Wikipedia, the free encyclopedia.

By the way, this is an example of conversational entropy…if you talk to people long enough the subject matter will inevitably fall to the lowest common denominator, which is usually bodily functions of one sort or another…seeing as well we all have bodies…and functions…