Will eating processed meat give you cancer?

How does smoking really compare to eating bacon sarnies and having a barbie in terms of cancer risk?

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Both smoking and eating processed meat have been identified as cancer risk factors by the World Health Organization (WHO). This does not mean that a smoker or someone who eats processed meat will get cancer, but it increases the likelihood that they will.

Smoking is a very well-known risk factor for several types of cancer, including lung, throat, mouth, bladder, pancreas, and kidney cancer. Smoking increases the risk of cancer because it contains carcinogenic substances that directly damage DNA and other cellular processes in the body that ultimately lead to the uncontrolled cell replication that leads to cancerous tumour growth.

Processed meat has also been classified as a Group 1 carcinogen by the WHO, which means that there is sufficient evidence to conclude that it causes cancer in humans. Processed meat includes meat that has been preserved by smoking, curing, salting, or adding preservatives. Examples of processed meat include hot dogs, bacon, ham, sausages, and deli meats. However, the mechanism by which eating processed meats increases one’s cancer risk is unclear. There could be a connection between the nitrites and nitrates used to preserve some meats but these are not present in all meats and there is no definitive evidence that such preservatives generate carcinogens in the gastrointestinal tract.

Indeed, while nitrites and nitrates have been shown to form potentially carcinogenic N-nitroso compounds (NOCs) in the gut, the concentration of these compounds in processed meat is relatively low, and other factors may also contribute to the cancer risk associated with processed meat consumption. For example, cooking methods such as grilling and frying can generate carcinogenic compounds, and high-temperature cooking of meats has been linked to an increased risk of cancer. In addition, some studies suggest that the high levels of saturated fat and cholesterol in processed meat may contribute to cancer risk. It is perhaps more likely that high processed meat consumption is associated with unhealthy dietary and exercise patterns, such as a sedentary lifestyle and a higher intake of calories.

In terms of cancer risk, it is difficult to directly compare smoking and eating processed meat. Both increase the risk of cancer, but they do so in different ways and to different extents. Smoking is a more significant risk factor for lung cancer than processed meat, while processed meat may be a more significant risk factor for colon cancer. It is important to note that the risk of cancer from smoking and eating processed meat is also influenced by other factors, such as the frequency and quantity of consumption, as well as an individual’s genetics, lifestyle, and other environmental factors.

Limiting one’s consumption of processed meat and not smoking could be key to reducing one’s personal risk of getting cancer and other health problems. It is perhaps worth adding that alcohol is also a major risk factor for cancer.

Saving the Pioneer Spirit

I’m definitely cracking open a bottle of Prosecco tonight having just repaired the CD player on our 24-year old Pioneer stereo that had all but been consigned to the scrapheap a decade ago and usurped by twee little speakers and media player docking stations and such. I was clearing my home office-studio cupboards ahead of redecorating and thought I’d give the old Pioneer once last chance. Set up the hefty two-foot speakers and plugged it all in, FM radio, twin cassette player and vinyl turntable…and, of course the CD player…

old-pioneer-stereo

Now, the radio always was hissy, so that’s a bit of a waste of space. The turntable? Well all our vinyl LPs are in boxes in the loft and it looked like the stylus was bent, so perhaps not. And cassettes, I have a few (hundred), but I couldn’t be bothered to unearth those either. Instead, I just plugged in an aux wire and connected it tomy phone as a test. Played the three songs I recorded and produced for Simon O yesterday (more on that later). The sound was as good as ever and every nuance and emotion from Simon’s singing and playing shone through, as did all the mistakes and the bits where I’d fluffed the mixing…beats a tiny docking station hands down and hands in the air.

Aah, but what about the broken CD player, you ask? Well, I thought I’d take a look at that. So I disconnected it from the mains, took the cover off, which required the smallest Allen key I could find and I peered inside. Oddly, there was not a speck of dust, the printed circuit boards looked pristine (the opposite of what you find if you open up an old desktop computer). My first thought for a repair was to give the laser lens a clean with some clear, colourless vinegar, that’s the usual first tip…but I couldn’t see the lens.

I lifted it up to give it a closer inspection to see if I couldn’t get a cotton bud dipped in vinegar into some nook or cranny to wipe across the lens and there was a little rattling sound and out rolls a shiny free-rolling piece of plastic glinting under our new low-cost, but high-bright LED bulbs! At least I now knew exactly why the CD player wasn’t doing what it says on the tin that it’s supposed to do. At this point the whole laser unit had to come out so I could glue the lens back into its rightful place.

Eventually, I had it all back together stuck an old favourite CD (a little bit of Bob Mould’s Sugar back in the cartridge and pressed play…the CD was spinning, the track time was progressing but there was no sound. Darnit. the CD was well worn and scratched. So I plucked out some Otis from our collection, some scratches but a lot cleaner than the Mould, and put that in the cartridge, same result.

Sad face.

Ah, but hold on, that tape wire that connects the CD to the amp, that’s just a control wire isn’t it? I remember now. It’s not the audio out from the CD player. So, off to my big box of wires and connectors to pluck out a pair of red and white RCA audio cables (there’s usually a yellow one these days for video). Stripped away the yellow strand, plugged red to red and white to white. Pressed play again and…and…the smooth sound emerges: “Sittin’ in the morning sun, sitting ’til the evening comes…” Yay. Fixed. The Cottenham Repair Cafe crew would be proud.

pioneer-spirit

One more job to do…dig out our multitude of old CDs from wherever they were all secreted with the (temporary) demise of our CD player and the advent of the docking station and go a little old school with a little more of Mr Redding’s wondrous voice and a couple of glasses of the sparkling stuff. Oh, I just heard a cork popping, Mrs Sciencebase must’ve heard my “cheers”!

Science isn’t everything, but it’s a lot

Those in science and those without often have a different perspective on how knowledge is formed. Indeed, those people in mathematics perhaps have yet another perspective, mathematics requiring an axiomatic and deductive approach that generates definitive proofs such as those that demonstrate the irrationality of pi, e and the nature of the square root of -1, the Pythagorean rule for right-angled triangles.

Science, by contrast, requires observations of phenomena and an inductive, empirical approach that explains them giving us theories that can predict other phenomena and yet are perpetually awaiting the observation that shows up the limitations of said theory or at least requires it to be revised. There will never be an observation that overturns a solid mathematical proof. This is not to say that gravity, evolution, the second law of thermodynamics are “just” theories. Newton’s theories of forces embodied in his laws of motion are not overturned by Einstein’s theories of relativity they are refined at the upper extremes of speed, mass and distance. But, whereas the square root of -1 will always be the imaginary number “i”, there may come a day when what goes up, doesn’t necessarily come down again. Any attempt to prove that science leads to certainty leads to the mistaken understanding that scientific methodology is mathematical and provides that kind of proof. But, just to reiterate its very nature does not imply that the theory of gravity, is “just” a theory.

Then, there are the theories of society, economics, history, art, the humanities.

Historical events in Europe through the last centuries has led to a conflict between science and religion and the notion that science somehow displaces religion. Rationally, from the scientific perspective it does. But, religion by definition is beyond “this world” and so the observations and theories are not, from the religious perspective, subject to validation by science.

It is a dangerous assumption that science is the only valid body of knowledge. It isn’t unless we imagine that aesthetics, morality, emotion and faith can be digested and distilled too. Maybe they can, we just need a sufficiently sophisticated brain scanner to unravel the neurochemical equations. But, as it stands, the application of the scientific method to the humanities, the social sciences, does not help us understand our feelings..

Writing in the International Journal of Pluralism and Economics Education, mathematician and economist Asad Zaman of the Pakistan Institute of Development Economics, argues that the two big mistakes – conflating mathematical and scientific proof and assuming that the scientific method works in the social sciences – have crippled the development of our understanding of human beings and societies, but more to the point he is worried that social scientists using the term science in their field is just plain wrong.

“The failure to understand the basic realities of human experience has led to many disasters, and needs to be rectified by correcting this double mistake,” he argues. Fundamentally, “science is not useful for the study of subjective, internal human experience,” says Zaman. He’s not arguing against science, he’s arguing against the idea that the scientific approach can provide definitive answers in areas that are to all intents and purpose off limits to that approach. Indeed, there is a huge range of important questions that science cannot answer such as those pertaining to social economic, political, moral, aesthetic problems and issues.

In order that the humanities move forward and we are able to edge towards answers to the more philosophical questions surrounding our place in the universe. We must recognise that while science provides rational explanations and solutions for countless problems we must again incorporate human experience into the admissible body of knowledge to make true progress. It’s not just that social scientists should stop deifying science and adopting the hubristic stance of imagining that we can play god, they should embrace what science cannot do, seek the questions it cannot answer, and accept its limitations in the face of the human condition.

I asked Zaman for a comment on my take on his paper: “Science is not damaged by its uncertainty and its incompleteness,” he told me. “Scientific theories continue to be extremely useful and provide us with tools of extraordinary power.” He added that, “There is no need to prove science leads to certainty and will provide us with all possible knowledge. However, for psychological reasons arising from peculiarities of European history, this need was felt, and the attempt was made to prove that science is certain – the deification.”

The implications of recognising how science works and how it does not provide irrevocable universal knowledge is that scientific laws must remain valid from Alaska to Altair from 1 million years BC to the year 3000, beyond and before, beneath, between and behind. “However,” adds Zaman, “human experiences for, and solutions to social problems of today must be derived from studying the frameworks of consciousness we live in today, which are not the same as those of yesterday and will be different tomorrow.” He explains that, “The most important problems we face as human beings relate to our unique experiences – such the impending environmental catastrophe – and also relate to subjective experiences outside the scope of science. Thus, our most important problems relating to our experience reality, meaning of life, compassion, truth justice and how to achieve them, cannot be studied scientifically.”

Zaman, A. (2015) ‘Deification of science and its disastrous consequences’, Int. J. Pluralism and Economics Education, Vol. 6, No. 2, pp.181—197.

*Science and scientists well recognise the limitations of their endeavours and mostly do not self-deify. Indeed there was a paper some time ago discussing why it’s good for scientists to be stupid. As I see it, scientists know full well that mathematical proof is entirely different from scientific proof and that questions of the human condition – ethics, morality etc – cannot be answered by science. What science can do, however, is provide the information and explanations for a lot of the problems and the wonder we experience and give us the means to create the technology to deal with them. It is those outside science who adopt a scientific stance that are making a rod for their own back.

It is often those exclusively entrenched in the humanities who imagine that science does not recognise its limits and make assumptions about scientists themselves and their seemingly cold logical worldview. I know a lot of knowledgeable scientists interested in a wide range of arts and recognising the human condition, more perhaps than artists with a penchant or understanding of science who aren’t necessarily able to flip the art-science coin and recognise the beauty within science itself. But, again, the concern is mainly that those outside science who grasp at scientific principles for their humanities work. There is, after all, no application of quantum mechanics to the gender debate, no solution to racism in the second law of thermodynamics, and despite its name, relativity theory is not going to address issues of sexuality and human interaction.

Twenty years on the web

If I remember rightly, I posted my first web page this month, twenty years ago. It was just a glorified .sig, but I began to add hyperlinked news stories to the server and that page would ultimately become Elemental Discoveries, which was arguably the first chemistry news website. Regular readers will know that this eventually morphed into sciencebase.com in July 1999.

Just sayin’

Blacker than black material

The perfect black body exists only in textbooks, a theoretically thermodynamic thought that suggests that all energy hitting the surface of such a body is absorbed and subsequently emitted with no energy lost. In reality, such an entity does not exist, but by taking inspiration from what seems to be the polar opposite, the whiter than white Cyphochilus beetle, researchers in Saudi Arabia have ripped a leaf from that textbook to make a material that is the blackest ever synthesised.

black-body

I explain in the magazine Chemistry World how Andrea Fratalocchi of the King Abdullah University of Science and Technology (KAUST) and colleagues suggest that their broadband light absorbing material could open up new approaches to energy-harvesting, optical and optoelectronic devices.

I asked Silvia Vignolini of the University of Cambridge for her thoughts on the research, as an expert on natural and biomimetic photonic structures. This is what she had to say:

Natural systems are a great inspiration for scientists, [the researchers] demonstrate how the Cyphochilus beetle taught us that a continuous interconnected network of scattering elements allows us to achieve an angular- and wavelength-independent response. This general concept can be applied for improving white as well black materials. However, nature is still ahead of us regarding optimization, when we compare results in a film-like geometry, natural materials outperform artificial structures in terms of density and weight, i.e. less material is needed to obtain similar performance. Some butterflies directly optimize darkness to regulate their body temperature, it would be interesting to have a one-to-one comparison of the structural and material effects to test how well we are doing in comparison with nature when designing the geometry of novel optical materials.

This area of research, biomimetic photonics, which aims to emulate the wonderful optical and visual properties of beetle exoskeletons, butterfly wings, the opalescent sheen of mother of pearl and many other natural materials, is growing steadily. Each iteration blurs the lines between what nature has had millions of years to achieve through evolution and what scientists can do in the laboratory. It is leading is along new avenues of fundamental research as well as opening technological doors for the kinds of systems, solar-energy conversion, optical computers, that will help us solve many of the problems we must face in the 21st Century.

You say you wanted evolution

Mobile apps and interactive social media are all well and good, but sometimes you just want to get out the drawing pins or Blu-tac and put a poster up on your wall, classroom, office, den, wherever. If you’re intrigued by the Tree of Life, then check out Evolution Posters, detailed and scientifically accurate with the modern, the extinct, the missing link for empty wallspace.

Evolution-Poster

Depression and diabetes

There’s a new hashtag on the block #StigmaFighter. It’s a good idea. We should all be stigma fighters. One of its campaigns uses the following:

Depression is a serious illness, just like diabetes or heart disease. Expecting positive thinking to cure depression is like expecting a person with diabetes to lower their blood sugar levels by thinking happy thoughts.

diabetes-depression

Well, the sentiment is good. Depression is serious. And, it is difficult to treat. There is an important point to be made. However, after decades of self-help books and allusions to the power of positive thinking, battling against other diseases with the power of our minds etc, is it actually any surprise that people might assume that someone with depression could be treated by suggesting positive thinking? The whole “chin up, old chap” approach…

It’s not like trying to treat diabetes by suggesting that the patient think happy thoughts. It’s more like treating the disease by telling the patient not to think about cakes and sweets when their blood sugar is too high and conversely to think about cakes and sweets more when it is too low.

Whereas diabetes is all about the chemistry of pancreatic activity and insulin, depression in contrast is a mental illness, there is a psychological component, even if the underyling chemistry is that of the brain and its neutrotransmitters, such as serotonin, dopamine.

Of course, the “chin up” technique doesn’t work, nor does “stiff upper lip” self-therapy. But, the point is that it’s really no surprise that people, including general practitioners, think it might…

SmoothHound – a new angle for wireless guitarists

I’ve been casting around for a good way to avoid the trip hazard that is the generic guitar lead, they’re tiresome in my home “studio” where wires are everywhere, but, also a mission critical problem in the small venues I’ve gigged at, especially when fellow musicians tread on them mid-song and suddenly I’m unplugged and silent…

Turns out there’s a local company here in Cambridge, SmoothHound, who have weighed in with a clean and lean piece of kit that could be the best catch for the home musician, street buskers, the semi-pro (and probably even) pro gigging players. Their classic Wireless Guitar System uses digital wireless audio to get rid of the wire but avoids that whole bulky belt pack transmitter technology too. In fact, having tried it out in a live setting a couple of times, I can vouch for the fact that you almost forget it’s there, it just jacks into your guitar (electric, electro-acoustic, bass, whatever) almost out of sight and out of mind. The receiver simply plugs into the desk or your amp and sends out rich, high-fidelity sound, that picks up every nuance of your tone without any of the nasty hiss of the outmoded VHF-type systems out there.

SmoothHound-Wireless-Guitar-System
It’s all very easy to setup. Just plug it in and switch on. The system automatically adapts to the environment and avoids interference from any nearby Wi-Fi gadgets. Moreover, the SmoothHound has an ARM chip in the transmitter and in the receiver to encode and decode the signal from your guitar without any loss of quality and does all that pretty much instantaneously giving it a very low latency, which worked perfectly playing live with my electro-acoustic Taylor  six-string recently). Speaking of which, the system has a range of about 60 metres, which is more than adequate for your home studio or the upstairs room at the local pub.

SmoothHound-Wireless-Guitar

The two AAA batteries in the transmitter last about 15 hours, which would be plenty even for Springsteen, and the mains-powered receiver has a charge indicator for transmitter battery strength so your guitar tech (yeah, right) knows when to run to you with replacements, preferably not mid-song. Oh, and here’s a top tip: being wireless at your soundcheck means you can step away from the performance area and listen to the full band (and you), which is a very useful thing to be able to do when setting up!

I’ve been fishing for an angle for this review and so I’m reeling in a few puns I’ve hooked just to say that the SmoothHound frees you entirely from the guitar lead that so often gets snagged and tangled while you play whether you’re gigging or riffing on a chair at home with your Marshall cranked up to 11. Highly recommended. Weigh up SmoothHound here or sail on over to amazon to land one right now.

Worrying about microbeads?

Are you worried about the microbeads used in your facial scrub and toothpaste? Risk Bites takes a look at where these tiny polythene beads end up and explains why experts are becoming increasingly concerned about their potential environmental and health impacts, along with micro plastic particles.