French researchers have now demonstrated a way to circumvent one of the main problems associated with cellular imaging and can obtain nanomolar concentration readings even for complex biological samples using their approach.
The method has led to an extension of the use of spectroscopy and spectro-imaging to many more parameters associated with cellular activity in both cultured and xenografted cells, and living tissues. No other analytical technique is available that can analyse tissue sections without embedding, fixation, or reagents adding, at the resolution and sensitivity obtained by the team.
Read on…